The song is the title track from Bruce Springsteen's 11th studio album. The name comes from John Steinback's The Grapes of Wrath.
The One Campaignwas started by U2 front-man Bono. The organization seeks to end extreme poverty.
Other notable artists have covered the song including Rage Against The Machine. Springsteen does a pretty great version of the song with Rage Against The Machine guitarist Tom Morello. Watch that after the Mumford/Costello version.