The Red Hot Chili Peppers with John Frusciante on guitar were one of the best live bands to ever exist. They're still pretty awesome with Josh Klinghoffer on guitar, but Frusciante is one of the best of all time.
John Frusciante joined the Red Hot Chili Peppers in 1988. He was replacing the late Hillel Slovak. John was an 18-year-old who idolized the band and Slovak. Frusciante and the Chili Peppers released Mother's Milk in 1989 and Blood Sugar Sex Magik in 1991.
Blood Sugar Sex Magik launched the band into superstardom. But, John struggled with success and left the band 1992. He developed serious drug habits and spiraled into depression (if you've seen images and video of John Frusciante during this time, they're heart breaking).
Frusciante could easily be dead. But, he somehow battled back from addiction and rejoined the Red Hot Chili Peppers in 1998. Over the next several years, John and the Chili Peppers released three albums and Frusciante also released many solo projects. He left the band again, but this time to focus on solo work.
It's easy to spend a substantial amount of time watching YouTube videos of Frusciante era Red Hot Chili Peppers performances.
One clip that is particularly attention grabbing is the one below. It's a performance of Don't Forget Me from 2002's By The Way album. The song was never released as a single, but became a crowd favorite at concerts.
Watch the video. It's one of the best live guitar performances. Ever.